Girl starts school after rare disorder transplant

A woman and a young girl seated at a wooden dining table indoors. The woman  is wearing a pink top and the girl a pink polo shirt. School-related papers and a pencil case are on the table, with wooden chairs and patterned black-and-white comic-strip wallpaper visible in the background.

A four-year-old girl who spent six months having hospital treatment for one of the UK's rarest genetic conditions is now preparing for her first day at school.

Autumn, from Helperby in North Yorkshire, was diagnosed at 18 months old with Hyper-IgE syndrome, a condition which affects the immune system.

She underwent a successful stem cell transplant from a donor in Germany in December and isolated in hospital for more than a month afterwards, with Autumn now ready to begin the next phase of her young life.

Louise, her mother, said: "It was all really hard. She wasn't allowed to leave the hospital room. We could all leave, but we couldn't go and live our normal lives."

According to the charity Immunodeficiency UK, common features of the condition are "severe eczema, increased susceptibility to infections and markedly raised levels of immunoglobulin E (IgE)".

Autumn underwent chemotherapy to destroy existing cells, with them later replaced through a bone marrow transplant.

Because of vulnerability to infection, she spent more than 30 days living in a "bubble" only her parents could enter at Great North Children's Hospital in Newcastle.

Young girl lying in a hospital bed, covered by a purple patterned blanket, giving two thumbs up. Medical monitoring equipment is positioned beside the bed.

Louise said Autumn, who starts school on Tuesday, is looking forward to her next chapter.

"There's been no worry or lack of confidence or anything, which is amazing," she said.

Describing the impact of the successful transplant, Louise said: "It's like being reborn. You do all the firsts again.

"Now she can eat in a restaurant, go to a supermarket, now she can go and play with friends.

"All of that has just been incredible and she's taken it all in her stride."

Autumn is a finalist in the Young Hero category in this year's BBC Radio York Make A Difference Awards.

As part of her recovery, she followed in her mother's footsteps and took up kickboxing at a club near Easingwold, with her instructor describing her as "a fearless breath of fresh air".

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Original source Girl starts school after rare disorder transplant

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