The Reds endured a frustrating trip to Brentford on Saturday despite picking up a turnaround 2-1 victory, with both Szoboszlai and Frimpong forced off with injuries.

Speaking ahead of the Villarreal match, Iraola confirmed the pair will both miss tonight’s fixture, with Frimpong facing several weeks out but Szoboszlai’s issue deemed less serious.

As such, Ryan Gravenberch is reinstated into the midfield here, after he missed the Brentford trip due to serving a suspension.

He will slot back into the centre of the park at Anfield, partnering Alexis Mac Allister, while Trey Nyoni is a surprise starter.

Gakpo also makes his comeback on the left flank, while Lewis Koumas and Rio Ngumoha complete the front three.

Ronald Araujo spoke alongside Iraola at the pre-match press conference, suggesting he was in line to start, and he slots in at right-back.

Kostas Tsimikas comes in at left-back, while Virgil van Dijk and Jeremy Jacquet shield Alisson.

Alisson; Araujo, Jacquet, Van Dijk, Tsimikas; Gravenberch, Mac Allister, Nyoni; Gakpo, Koumas; Ngumoha

: Barcola, Chambers, Danns, Gomez, Isak, Kerkez, Laffey, Mamardashvili, McDonnell, Wirtz, Woodman

Szoboszlai, Frimpong, Ekitike, Leoni, Bradley

Time and date: 8pm BST on Tuesday October 20, 2026

How to watch: Amazon Prime