The radical new breast cancer trials to cut gruelling radiotherapy sessions by two-thirds

Women with early-stage breast cancer could be spared multiple rounds of gruelling radiotherapy under a “breakthrough” cancer trial.

More than 1,000 people have joined a Government-funded trial testing whether breast cancer radiotherapy can be safely cut from three weeks to just five days, with women potentially spared 10 hospital visits.

The “FAST-Forward Boost” trial is running at 39 hospitals across the UK and will test a shorter course of radiotherapy with an additional targeted dose, known as a boost, to help stop breast cancer returning. 

A woman lies back on a couch with her arm over her eyes

Does testosterone really help improve menopause brain fog?

There is “insufficient” evidence to back the claim that testosterone can improve brain fog and memory symptoms linked to the menopause, a new study suggests.

Social media is “flooded” with claims that testosterone can improve these symptoms in menopausal women, experts said.

What you need to nkow

While there is anecdotal information that testosterone can help, experts stressed that there is currently not enough evidence to establish the effect. Experts at University College London said testosterone prescriptions have increased in the UK, reflecting growing interest in its role during menopause.

The team reviewed five studies which looked at whether testosterone can improve memory in post menopausal women.

3 min read

5 min read

A closer look at the detail

244 women

Some 244 women with an average age of 57 involved in the review were given either a placebo or testosterone at varying levels.

  • The research team did not find significant improvements for cognitive function among participants taking testosterone.
  • “The findings should be interpreted as insufficient to establish an effect, rather than as evidence of no effect,” the authors wrote in the journal Reproduction And Fertility.

The expert view

While there may be some anecdotal evidence for this in perimenopausal women, we cannot claim testosterone improves cognition during menopause without further evidence. More research is needed to understand any links between  and brain health.

Professor Aimee Spector, senior author of the study and director of the UCL Menopause Mind Lab

Psychologists sound alarm over chatbots ‘harmful’ mental health advice

Digitally generated image

Psychologists have raised concerns about unregulated AI chatbots providing “unqualified and harmful” information to people seeking mental health advice.

It comes as a British Psychological Society (BPS) survey found that practitioners have seen a 49 per cent rise in the number of patients using AI for support in the last 12 months.

What did the survey find?

  • One member told the survey they are worried people are turning to technology as it feels “safer”, but warned there is a risk of increasing isolation that can impact wellbeing.
  • The BPS poll of 197 psychologists, counsellors and psychotherapists found seven in 10 are somewhat or very concerned about clients using AI for mental health support.
A man with an open head and a brain hovering above

A closer look at the figures

80%

told the survey they are concerned clients are becoming overly reliant on the technology, while around three quarters (76 per cent) said it is negatively affecting client wellbeing.

  • The BPS poll comes after a survey of 2,000 children aged 11-17 by Barnardo’s and the National Counselling and Psychotherapy Society (NCPS) found more than four in 10 (43 per cent) had used AI for advice or emotional support.

The expert view

This research shows there is real cause for concern for those that use AI for mental health therapy, and that concern is coming directly from psychological practitioners on the frontline providing vital in-person support. The risk of unregulated open access AI chatbots providing unqualified and harmful advice remains very real.

Dr Laura Dean, president of the BPS
Digital generated image of african american ethnicity young man wearing suit standing on purple ramp and looking to multiple message chat icons. Artificial intelligence chatbot communication concept.

Russell Brand’s wife hails ‘kind’ husband but tells court he cheated when dating

Laura Brand, wife of British actor and comedian Russell Brand arrives at Southwark Crown Court during the third week of Russell Brand's trial on charges of rape and sexual assault involving six women between 1999 and 2009, which he denies, in London, Britain, October 29, 2026. REUTERS/Hannah McKay

Russell Brand’s wife Laura Brand has told his rape trial her husband is “caring” and “kind” and there is honesty at the centre of their marriage.

What Laura Brand told the court

She said they rekindled their romance in 2015, married two years later, and they now have three children together.

4 min read

3 min read

What the court heard

Russell, my husband, is caring, he is kind, he is a wonderful father to our children. He is an amazingly attentive husband. He has got an eye for detail I’ve never known before. The way he treats me is to really know me, I feel very seen by him in every way. I love him very much.

laura brand
British actor and comedian Russell Brand, accompanied by his wife Laura Brand, arrives at Southwark Crown Court for a two-day pre-trial hearing ahead of his Crown Court trial where he faces seven charges of rape and sexual assault relating to six women, in London, Britain, October 6, 2026. REUTERS/Hannah McKay REFILE - ADDING ID
  • Laura said she knew about his reputation before they met and she learned while they were dating that he had been having sex with other people.
  • She said they stayed friends as Brand had a brief marriage to singer Katy Perry, and they got back together as a couple in 2015.
  • Asked if she was “aware of his promiscuity” during their time apart, she said: “I was very aware of it. I could read about it regularly in the papers.”

3 min read

A closer look at the detail

During his wife’s evidence, Brand could be seen smiling and laughing at times, and he appeared to be mouthing words towards his wife as she talked about his 2024 baptism.

Court artist sketch by Elizabeth Cook of Russell Brand appearing during jury selection??at Southwark Crown Court, London, where he faces three charges of rape, indecent assault, and three counts of sexual assault, relating to six women. Picture date: Monday October 12, 2026. PA Photo. Photo credit should read: Elizabeth Cook/the Press Association
LONDON, UNITED KINGDOM - OCTOBER 12: Russell Brand, accompanied by his wife Laura Brand (not seen), arrives at Southwark Crown Court in London, United Kingdom, for a preliminary hearing over rape and sexual assault charges against him, on October 12, 2026. (Photo by Zeynep Demir/Anadolu via Getty Images)

Laura Brand’s evidence was briefly interrupted when defence barrister Ian Winter KC attempted to ask for her view on the “truth of the allegations”. Prosecutor Riel Karmy-Jones KC interjected, and the judge pointed out she is not an expert witness.

What we have learned so far

Court artist sketch by Elizabeth Cook of Riel Karmy-Jones KC cross examining Russell Brand in the dock at Southwark Crown Court, London, where he faces three charges of rape, indecent assault, and three counts of sexual assault, relating to six women. Picture date: Wednesday October 28, 2026. PA Photo. Photo credit should read: Elizabeth Cook/Press Association

Brand faces claims that he raped and sexually assaulted women over the course of 10 years of his showbiz career.

On Wednesday, he insisted consent is “non-negotiable” and told jurors it is “more important than sex itself”. He denies three charges of rape, three counts of sexual assault, and one count of attempted indecent assault.

4 min read

How weight-loss jabs boom is putting waste workers at risk

The rising popularity of injectable weight-loss drugs like Mounjaro and Wegovy means more used needles are turning up at recycling centres – and their bosses have warned this is putting workers at risk of infection and serious injury.

What is the issue?

Used needles should always disposed of through a dedicated clinical waste service.

Woman using injection pen to administer weight loss drug - stock photo
File photo dated 20/01/15 of Rubbish and recycling bins lining a street. New rules for household waste and recycling have come into force as part of efforts to standardise collections across England. Issue date: Tuesday March 31, 2026. PA Photo. Starting from Tuesday, households will now separate their waste into a maximum of four different bins for waste collectors to pick up ??? one for food and garden waste, one for paper and card, one for dry recyclables (such as glass, metal and plastics) and one for general non-recyclable rubbish. Photo credit should read: Steve Parsons/PA Wire

But a large number of weight-loss needles are being dumped in household bins, the BBC reports.

Waste site workers are regularly being pricked by them, putting their health at risk. 

What should you do to help?

A large pile of garbage inside a waste management recycling facility in Sherborne, Dorset. June 2025
  • Weight-loss drug users have been urged to speak to their GPs or pharmacies about obtaining a sharps bin.
  • Whatever you do, never put a sharps container or loose needles in your recycling bin.

4 min read

Recycling boss voices concern

There are safe disposal routes for needles but the worst place to put them is in your recycling. It ends up in facilities like ours where it will be touched by people and that’s inherently unsafe

Richard Dobbs, managing director of Sherborne Recycling
A woman holds an Ozempic needle shot pen in this photograph taken in Warsaw, Poland on 19 November, 2023. German regulator BfArM is considering banning the export of the Ozempic weight loss drug, manufactured by the Danish Novo Nordisk company due to shortages caused by popularity in the United States. Ozempic is commonly prescribed to patience with diabetes or a risk or getting diabetes however Ozempic is also effective as a stand alone weight loss solution. (Photo by Jaap Arriens/NurPhoto via Getty Images)

Poundland on brink of administration – what we know

Knives will no longer be available in Poundland's 755 branches (PA)

Poundland has filed to appoint administrators, threatening the future of around 12,000 workers.

Court filings show that the retailer filed a notice of intention to appoint administrators on Thursday, which will give the business 10 working days of breathing space from creditors to secure a potential rescue deal.

Despite enormous efforts it has not been possible to identify an acceptable offer for the business as a whole. The process has however attracted several established retail operators who have made formal offers. Collectively these cover a significant part of the business.

Barry willams, Poundland’s managing director
A member of the public walks past a closed down Poundland shop, a popular value bargain goods chain in the UK, as warnings come from retail and hospitality experts that the Bank of England's interest rate hikes threaten to kill the country's high street on 3rd August, 2023 in Margate, United Kingdom. (photo by Daniel Harvey Gonzalez/In Pictures via Getty Images)

What you need to know

  • Advisers are still in talks with parties interested in buying the brand and swathes of stores.
  • Poundland stressed that all its stores remain open and trading as normal despite the insolvency process.
  • It comes after owner Gordon Brothers rejected a takeover offer from Irish real estate firm Martin Property Group, which management named as their preferred bidder earlier this month.

3 min read

A closer look at the detail

  • Gordon Brothers – which only bought Poundland last year for £1 – launched a sale process for the retailer at the start of September.
  • Poundland currently runs around 600 stores across the UK.
  • Wilko and The Range owner CDS Superstores, Poundstretcher owner Fortress and TG Jones owner Modella are all understood to be interested in buying parts of the Poundland business.
  • However, deals are unlikely to include all Poundland stores and some jobs are likely to be affected.

Girl, 8, injured in wolf attack at German wildlife park

An eight-year-old girl has been left seriously injured after being attacked by a wolf at a wildlife park in Germany.

What happened?

Following a wolf's attack on a child, the entrance to the Johannesmuehle Wildlife Park has been cordoned off with barrier tape in Baruth north of Berlin, Germany, Wednesday, Oct. 28, 2026. (Carsten Koall/dpa via AP)
  • The girl, who has not been named, was attacked at the Johannismühle wildlife park near Berlin.
  • The facility had been holding a special event for children at the time of the incident, the Associated Press reported.

3 min read

What do we know?

  • The girl was attacked before the park opened on Wednesday, German media reports.
  • She was rushed to hospital by helicopter after the incident.
  • The park has been temporarily closed and is set to reopen on 2 November.
  • Johannismühle’s website states it offers small group tours where there is an opportunity to “feed wolves”.
  • There are no reports of anyone else being injured.

The background

Yorkshire Wildlife Park remains closed today, October 12 , 2026, after a man was fatally attacked by a tiger. // The 175-acre zoo located near Doncaster, South Yorks., was shut on Saturday after a man - who has not been named - jumped into the animal's enclosure. Tragically, he was pronounced dead at the scene, South Yorkshire Police later said. A spokesperson from the popular family-friendly park confirmed it was closed yesterday (Sunday), with the park's website detailing that it will also be closed today (Monday). Photo released 12/10/2026

The news comes after William Chapman, 24, was fatally mauled by a tiger at the Yorkshire Wildlife Park earlier this month.

Senior coroner Nicola Mundy said Chapman had a history of mental illness, a diagnosis of schizophrenia and had suffered previous bouts of psychosis.

3 min read

It is hoped that reducing the rounds of treatment will improve patients’ quality of life and cut travel costs and time away from work and family, while also freeing up NHS capacity to treat more people.

The trial builds on previous research, and a similar approach has already been adopted for other conditions such as low- to intermediate-risk localised prostate cancer.

Researchers hope to recruit more than 4,000 people for the trial overall, with participants followed up for five years and results expected in 2033.

Radiotherapy for early-stage breast cancer is very effective but can be gruelling for patients due to treatment being required over several weeks, side effects and also the emotional strain.

Yvette Cooper, the Health Secretary, said: “This trial shows how the UK is using our world-beating research capabilities to pursue huge improvements and transformations in cancer treatment for patients in our NHS.

“This programme is aiming to radically shorten the treatment times for breast cancer – to support patients and save more lives. The UK is home to some of the best medical research and clinical expertise in the world, and this trial is the latest example of what we can achieve when we bring them together.”

Professor Lucy Chappell, the chief executive of the National Institute for Health and Care Research (NIHR) and the Department of Health and Social Care chief scientific adviser, said: “Playing a major role in tackling some of the biggest killers, including breast cancer, is at the very heart of what we do.

“For 20 years, the NIHR has invested in studies like the FAST-Forward Boost trial – funding high-quality research that transforms patient care in the NHS.

“We know the impact breast cancer treatment can have on patients and their families, and how the side effects of radiotherapy can affect people’s quality of life, even long after treatment has ended.

“Studies like this are crucial, as they aim to not only identify new treatment options which can be delivered swiftly and safely – but also minimise side effects, giving patients more time away from hospitals and with the people that they love.”

The trial is being led by the Institute of Cancer Research, London, and funded through the NIHR. 

The Government has also announced that Ashley Dalton, a Labour MP who has terminal breast cancer, has been appointed as an adviser on delivery of the National Cancer Plan.

Dalton resigned as a health minister in March to manage her health and treatment side effects.

She said: “It’s a real honour to be appointed the Government’s Cancer Adviser. Publishing the National Cancer Plan was a huge professional and personal achievement of mine and I have been determined to ensure that the commitments in it are driven forward.

“Now I can do this in a more formal way, working directly with the responsible minister, James Frith.

“My time as health minister taught me so much, and so has living with metastatic breast cancer. I want to use my experiences in the best way I can, to support the commitment in the National Cancer Plan that by 2035, three out of four people diagnosed with cancer will be cancer-free or living well with cancer after five years.”

The 39 hospitals taking part in the trial

  • The Royal Marsden Hospital, London
  • The Royal Marsden Hospital, Sutton
  • James Cook University Hospital, Middlesbrough
  • St. John’s Hospital, Livingston
  • Barts (St Bartholomew’s Hospital), London
  • The Beatson West of Scotland Cancer Centre
  • Dumfries and Galloway Royal Infirmary
  • St James’s University Hospital, Leeds
  • Bristol Haematology & Oncology Centre

Original source The radical new breast cancer trials to cut gruelling radiotherapy sessions by two-thirds

Back to home